CAB39L

Across TCGA pan-cancer cohorts, CAB39L mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CAB39L data layer compared with 21 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher CAB39L mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated CAB39L expression acts as an unfavorable survival marker, although some lineages such as PDAC and CCRCC show a favorable association.

PDAC, LSCC, and CCRCC are the cancer types where CAB39L mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	All	0.634	0.449	.001	38	view →
LSCC	OS	Quartile	II,III,IV	0.541	1.000	.011	12	view →
CCRCC	DFS	Quartile	III,IV	0.630	0.229	.037	5	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CAB39L–PDAC (OS)

Open the PDAC breakdown →