CAB39L

Across TCGA patient cohorts, CAB39L mutation is significantly associated with the RNA expression of many other genes, with 1,052 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAB39L-associated genes across cancer lineages are RNU6-380P, RN7SKP260, and RNU4-68P. Each is linked with CAB39L in more than 2 cancer types. Because this analysis shows association rather than direction, both CAB39L-to-partner and partner-to-CAB39L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-380P grouped by CAB39L-low versus CAB39L-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAB39L→partner) and Y-score (partner→CAB39L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNU6-380P →	+0.268	+5.733	<.001	.001	3	3
LUSC	RN7SKP260 →	+0.198	+6.102	<.001	.001	3	3
COAD	RNU4-68P →	+0.685	+3.408	<.001	.009	3	2
COAD	RN7SL508P →	+0.540	+3.289	.002	.008	3	2
COAD	RNU6-881P →	+0.292	+5.142	.005	.002	3	2
UCEC	RNU1-1 →	+0.171	+1.994	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,052 associations by consensus.

RNU6-380P by CAB39L expression — LUSC

Explore this box plot interactively →