CAB39L

Across TCGA patient cohorts, CAB39L mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAB39L-associated genes across cancer lineages are Ku80, ASNS, and Cyclin-E2. Each is linked with CAB39L in more than 1 cancer types. Because this analysis shows association rather than direction, both CAB39L-to-partner and partner-to-CAB39L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by CAB39L-low versus CAB39L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAB39L→partner) and Y-score (partner→CAB39L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.217	+1.691	.016	.014	3	2
UCEC	ASNS →	+0.507	+1.678	<.001	.023	3	2
UCEC	Cyclin-E2 →	+0.156	+2.087	.015	.005	3	2
UCEC	eEF2 →	+0.355	+2.459	.009	.019	3	1
UCEC	EGFR_pY1068 →	-0.202	-2.700	.036	.006	3	1
UCEC	ERK2 →	+0.201	+3.321	.006	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Ku80 by CAB39L expression — UCEC

Explore this box plot interactively →