CAAP1

Across TCGA patient cohorts, CAAP1 mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CAAP1-associated genes across cancer lineages are FASN, FOXO3a_pS318_S321, and Rab11. Each is linked with CAAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CAAP1-to-partner and partner-to-CAAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FASN grouped by CAAP1-low versus CAAP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CAAP1→partner) and Y-score (partner→CAAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FASN →	+0.536	+3.169	.013	.020	3	1
UCEC	FOXO3a_pS318_S321 →	-0.138	-3.169	.044	.020	3	1
UCEC	Rab11 →	-0.179	-3.169	.024	.020	3	1
UCEC	Src_pY527 →	-0.480	-3.169	.042	.020	3	1
UCEC	p62 Lck ligand →	+0.491	+3.009	.006	.019	2	1
UCEC	4E-BP1 →	+0.448	+3.169	.002	.020	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

FASN by CAAP1 expression — UCEC

Explore this box plot interactively →