CAAP1

Across TCGA pan-cancer cohorts, CAAP1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of CAAP1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where CAAP1 RNA is repressed in tumor relative to normal tissue. In most cancer types CAAP1 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

THCA, KIRC, and LIHC are the cancer types where CAAP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CAAP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	III,IV	−0.911	<.001	11	view →
KIRC	Male	III,IV	−0.714	<.001	11	view →
LIHC	Male	II,III,IV	+0.790	<.001	7	view →
STAD	Female	All	+0.497	.006	4	view →
LUAD	All	All	+0.244	.001	2	view →
LUSC	All	III,IV	−0.888	.030	1	view →
ESCA	Female	All	+0.809	.045	1	view →
KIRP	Male	All	−0.340	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

CAAP1–THCA

Open the THCA breakdown →