CA9

Across TCGA patient cohorts, CA9 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,497 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CA9-associated proteins across cancer lineages are PLOD2, ERO1A, and HK2. Each is linked with CA9 in more than 6 cancer types. Because this analysis shows association rather than direction, both CA9-to-partner and partner-to-CA9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CA9 versus PLOD2 in BRCA, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CA9→partner) and Y-score (partner→CA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PLOD2 →	+0.983	+2.308	<.001	<.001	3	7
GBM	ERO1A →	+0.755	+1.947	<.001	<.001	3	7
GBM	HK2 →	+0.641	+1.929	<.001	<.001	3	6
BRCA	PGK1 →	+0.307	+1.387	<.001	.001	3	6
BRCA	PFKP_S386 →	+1.764	+2.578	<.001	<.001	3	6
LSCC	LOXL2 →	+0.897	+1.746	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,497 associations by consensus.

CA9 vs PLOD2 — BRCA

Explore this scatter interactively →