CA8

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CA8 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,341 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CA8-associated proteins across cancer lineages are MLPH, ARFGEF3, and SGSM3. Each is linked with CA8 in more than 5 cancer types. Because this analysis shows association rather than direction, both CA8-to-partner and partner-to-CA8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CA8 versus MLPH in COAD, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CA8→partner) and Y-score (partner→CA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADMLPH →+0.870+1.487<.001<.00136
BRCAARFGEF3 →+0.557+1.629.001<.00136
LUADSGSM3 →+0.566+1.055<.001<.00136
HNSCELAPOR1 →+1.144+1.242<.001<.00136
HNSCHID1 →+0.535+0.725<.001<.00136
COADRAP1GAP →+0.826+1.618.002<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,341 associations by consensus.

CA8 vs MLPH — COAD

Per-sample scatter of CA8 vs MLPH in COAD (Pearson r = 0.38).

Explore this scatter interactively →

Exploration