CA8

Across TCGA patient cohorts, CA8 protein abundance is significantly associated with the RNA expression of many other genes, with 8,286 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CA8-associated genes across cancer lineages are PPARGC1A, PHYHIPL, and CDH3. Each is linked with CA8 in more than 3 cancer types. Because this analysis shows association rather than direction, both CA8-to-partner and partner-to-CA8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CA8 versus PPARGC1A in LUAD, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CA8→partner) and Y-score (partner→CA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PPARGC1A →	+1.610	+0.887	<.001	<.001	3	4
GBM	PHYHIPL →	+0.761	+0.559	<.001	<.001	3	4
BRCA	CDH3 →	-1.265	-0.604	.001	.002	3	4
UCEC	ELAPOR1 →	+3.077	+0.985	<.001	<.001	3	4
UCEC	MIR222HG →	-1.039	-0.637	<.001	.005	3	4
PDAC	CAPN9 →	+1.445	+0.432	.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,286 associations by consensus.

CA8 vs PPARGC1A — LUAD

Explore this scatter interactively →