CA8

Across TCGA cell cohorts, CA8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,796 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CA8-associated GO terms across cancer lineages are Regulation of myoblast fusion, Calcium ion transport, and Regulation of transcription initiation by RNA polymerase II. Each is linked with CA8 in more than 8 cancer types. Because this analysis shows association rather than direction, both CA8-to-partner and partner-to-CA8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by CA8-low versus CA8-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CA8→partner) and Y-score (partner→CA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of myoblast fusion →	+0.113	+3.386	<.001	<.001	3	9
STOMACH	Calcium ion transport →	-0.048	-1.238	<.001	<.001	3	9
LARGE_INTESTINE	Regulation of transcription initiation by RNA polymerase II →	+0.042	+1.023	<.001	<.001	3	9
STOMACH	Nucleic acid catabolic process →	+0.045	+1.289	<.001	<.001	3	8
STOMACH	Negative regulation of myoblast fusion →	+0.101	+1.402	<.001	<.001	3	8
STOMACH	Protein polyubiquitination →	+0.062	+1.302	<.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,796 associations by consensus.

Regulation of myoblast fusion by CA8 expression — LUNG_SCLC

Explore this box plot interactively →