CA7

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CA7 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,305 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CA7-associated proteins across cancer lineages are S100A12, PPP2R5D, and MMP8. Each is linked with CA7 in more than 2 cancer types. Because this analysis shows association rather than direction, both CA7-to-partner and partner-to-CA7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CA7 versus S100A12 in GBM, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CA7→partner) and Y-score (partner→CA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMS100A12 →-0.989-0.404<.001.00133
GBMPPP2R5D →+0.182+0.651.001<.00133
GBMMMP8 →-1.429-0.600<.001.00133
GBMS100A8 →-1.517-0.525<.001.00133
GBMS100A9 →-1.317-0.724<.001<.00133
GBMLCN2 →-1.355-0.537<.001.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,305 associations by consensus.

CA7 vs S100A12 — GBM

Per-sample scatter of CA7 vs S100A12 in GBM (Pearson r = -0.34).

Explore this scatter interactively →

Exploration