CA7

Across TCGA cell cohorts, CA7 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,454 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CA7-associated GO terms across cancer lineages are Nucleic acid catabolic process, Ribosome biogenesis, and tRNA transcription by RNA polymerase III. Each is linked with CA7 in more than 6 cancer types. Because this analysis shows association rather than direction, both CA7-to-partner and partner-to-CA7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleic acid catabolic process grouped by CA7-low versus CA7-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CA7→partner) and Y-score (partner→CA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nucleic acid catabolic process →	+0.066	+0.836	<.001	.002	3	7
BONE	Ribosome biogenesis →	+0.101	+0.667	.002	.003	3	7
BONE	tRNA transcription by RNA polymerase III →	+0.106	+0.634	.002	.009	3	7
BONE	Granzyme-mediated apoptotic signaling pathway →	+0.119	+0.807	<.001	<.001	3	7
LIVER	Proton motive force-driven ATP synthesis →	+0.093	+0.071	.003	.005	3	7
BONE	Purine ribonucleotide biosynthetic process →	+0.095	+0.674	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,454 associations by consensus.

Nucleic acid catabolic process by CA7 expression — BONE

Explore this box plot interactively →