CA4

Across TCGA patient cohorts, CA4 protein abundance is significantly associated with the RNA expression of many other genes, with 7,696 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CA4-associated genes across cancer lineages are FCGR3B, CEACAM3, and FPR2. Each is linked with CA4 in more than 4 cancer types. Because this analysis shows association rather than direction, both CA4-to-partner and partner-to-CA4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CA4 versus FCGR3B in HNSC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CA4→partner) and Y-score (partner→CA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FCGR3B →	+1.417	+0.628	<.001	<.001	3	5
COAD	CEACAM3 →	+0.869	+0.640	<.001	<.001	3	5
HNSC	FPR2 →	+1.251	+0.614	<.001	.001	3	5
BRCA	USHBP1 →	+0.641	+1.138	.007	.009	3	5
BRCA	CLDN5 →	+1.605	+0.950	.001	.002	3	5
COAD	VNN2 →	+0.871	+0.482	.006	.003	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,696 associations by consensus.

CA4 vs FCGR3B — HNSC

Explore this scatter interactively →