CA14

Across TCGA patient cohorts, CA14 mutation is significantly associated with the RNA expression of many other genes, with 2,834 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CA14-associated genes across cancer lineages are OR51T1, RNA5SP251, and PABPC1L2B-AS1. Each is linked with CA14 in more than 1 cancer types. Because this analysis shows association rather than direction, both CA14-to-partner and partner-to-CA14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR51T1 grouped by CA14-low versus CA14-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CA14→partner) and Y-score (partner→CA14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	OR51T1 →	+0.036	+5.505	<.001	.004	3	2
HNSC	RNA5SP251 →	+0.528	+5.578	<.001	.004	3	2
HNSC	PABPC1L2B-AS1 →	+0.039	+7.132	<.001	<.001	3	2
CESC	EIF1P2 →	+0.130	+4.503	.003	.005	3	2
BRCA	RNA5SP447 →	+0.440	+5.971	<.001	.002	3	2
BRCA	LARP1BP3 →	+0.057	+6.571	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,834 associations by consensus.

OR51T1 by CA14 expression — HNSC

Explore this box plot interactively →