CA12

Across TCGA cell cohorts, CA12 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,634 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CA12-associated GO terms across cancer lineages are Peripheral nervous system myelin maintenance, Regulation of ureteric bud formation, and Positive regulation of ureteric bud formation. Each is linked with CA12 in more than 7 cancer types. Because this analysis shows association rather than direction, both CA12-to-partner and partner-to-CA12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peripheral nervous system myelin maintenance grouped by CA12-low versus CA12-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CA12→partner) and Y-score (partner→CA12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Peripheral nervous system myelin maintenance →	+0.364	+2.873	<.001	<.001	3	8
OESOPHAGUS	Regulation of ureteric bud formation →	-1.316	-2.701	<.001	.001	3	7
OESOPHAGUS	Positive regulation of ureteric bud formation →	-1.316	-2.701	<.001	.001	3	7
OESOPHAGUS	Regulation of mesonephros development →	-1.316	-2.701	<.001	.001	3	7
BONE	Ceramide metabolic process →	+0.089	+2.420	<.001	<.001	3	7
LUNG_NSCLC_LUSC	Glycosphingolipid metabolic process →	+0.119	+2.428	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,634 associations by consensus.

Peripheral nervous system myelin maintenance by CA12 expression — BONE

Explore this box plot interactively →