CA11

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CA11 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,794 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CA11-associated proteins across cancer lineages are NRDC, GDI1, and CNTN1. Each is linked with CA11 in more than 5 cancer types. Because this analysis shows association rather than direction, both CA11-to-partner and partner-to-CA11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CA11 versus NRDC in BRCA, with a Pearson correlation of -0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CA11→partner) and Y-score (partner→CA11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCANRDC →-0.262-1.249.001<.00136
OVGDI1 →+0.304+0.914<.001<.00136
LSCCCNTN1 →+0.635+0.654<.001<.00135
GBMDNM1 →+0.644+1.142<.001<.00135
GBMPTPRS →+0.320+1.066<.001<.00135
CCRCCRPL5 →-0.209-0.638.001.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,794 associations by consensus.

CA11 vs NRDC — BRCA

Per-sample scatter of CA11 vs NRDC in BRCA (Pearson r = -0.29).

Explore this scatter interactively →

Exploration