CA11

Across TCGA pan-cancer cohorts, CA11 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated CA11 data layer compared with 3 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CA11 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated CA11 expression acts as an unfavorable survival marker, although some lineages such as LUAD and SKCM show a favorable association.

LUAD, SKCM, and PAAD are the cancer types where CA11 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	III,IV	0.734	0.479	.002	47	view →
SKCM	OS	Quartile	II,III,IV	0.829	0.617	<.001	44	view →
PAAD	DFS	Quartile	All	0.430	0.203	.001	40	view →
COAD	DFS	Median	All	0.300	0.772	<.001	38	view →
CESC	OS	Quartile	All	0.957	0.791	.002	34	view →
THCA	OS	Tertile	II,III,IV	1.000	0.954	.002	28	view →
LGG	DFS	Quartile	All	0.887	0.770	.001	22	view →
HNSC	OS	Quartile	All	0.828	0.687	.006	21	view →
READ	OS	Tertile	All	0.603	1.000	.008	14	view →
KIRP	OS	Quartile	II,III,IV	0.259	1.000	.011	14	view →
SCLC	DFS	Tertile	II,III,IV	0.885	0.271	.006	10	view →
ESCA	DFS	Quartile	All	0.379	0.586	.020	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

CA11–LUAD (DFS)

Open the LUAD breakdown →