Across TCGA patient cohorts, C9orf92 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,110 significant associations in total. STAD shows the largest number of these associations.

The most reproducible C9orf92-associated GO terms across cancer lineages are Nucleoside triphosphate biosynthetic process, Regulation of intrinsic apoptotic signaling pathway, and Proton motive force-driven ATP synthesis. Each is linked with C9orf92 in more than 15 cancer types. Because this analysis shows association rather than direction, both C9orf92-to-partner and partner-to-C9orf92 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf92→partner) and Y-score (partner→C9orf92) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Nucleoside triphosphate biosynthetic process →	+0.070	+0.150	<.001	<.001	3	16
ESCA	Regulation of intrinsic apoptotic signaling pathway →	+0.054	+0.109	<.001	<.001	3	15
ESCA	Proton motive force-driven ATP synthesis →	+0.078	+0.187	<.001	<.001	3	15
ESCA	Oxidative phosphorylation →	+0.052	+0.130	<.001	.001	3	15
ESCA	ATP synthesis coupled electron transport →	+0.072	+0.148	<.001	.001	3	15
STAD	ATP biosynthetic process →	+0.053	+0.112	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,110 associations by consensus.

Exploration

C9orf92 survival (RNA) · tumor vs normal (RNA) · all C9orf92 data types