Across TCGA cell cohorts, C9orf92 RNA expression is significantly associated with the mutation status of many other genes, with 194 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible C9orf92-associated genes across cancer lineages are NEB, COL4A4, and SLC26A4. Each is linked with C9orf92 in more than 3 cancer types. Because this analysis shows association rather than direction, both C9orf92-to-partner and partner-to-C9orf92 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf92→partner) and Y-score (partner→C9orf92) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	NEB →	+1.540	+0.068	.003	.003	3	4
PANCREAS	COL4A4 →	+5.000	+0.197	.006	<.001	3	3
BLOOD_Leukemia	SLC26A4 →	+4.539	+0.076	.007	<.001	3	2
BLOOD_Lymphoma	JAKMIP2 →	+4.058	+0.235	.009	<.001	3	2
UPPER_AERODIGESTIVE_TRACT	F7 →	+4.736	+0.456	.009	<.001	3	2
UPPER_AERODIGESTIVE_TRACT	CELSR1 →	+3.000	+0.187	.004	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 194 associations by consensus.

Exploration

C9orf92 survival (RNA) · tumor vs normal (RNA) · all C9orf92 data types