C9orf85

Across TCGA cell cohorts, C9orf85 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,107 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C9orf85-associated GO terms across cancer lineages are Proteasome regulatory particle assembly, CUT catabolic process, and snRNA catabolic process. Each is linked with C9orf85 in more than 7 cancer types. Because this analysis shows association rather than direction, both C9orf85-to-partner and partner-to-C9orf85 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proteasome regulatory particle assembly grouped by C9orf85-low versus C9orf85-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf85→partner) and Y-score (partner→C9orf85) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Proteasome regulatory particle assembly →	+0.081	+0.621	<.001	<.001	3	8
LARGE_INTESTINE	CUT catabolic process →	+0.123	+0.446	<.001	.003	3	8
SKIN	snRNA catabolic process →	+0.105	+0.684	<.001	.001	2	8
BREAST	7-methylguanosine mRNA capping →	+0.110	+0.612	<.001	<.001	3	7
SOFT_TISSUE	Host-mediated suppression of viral genome replication →	+0.081	+0.341	.001	.006	3	7
SOFT_TISSUE	Protein modification by small protein removal →	+0.060	+0.583	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,107 associations by consensus.

Proteasome regulatory particle assembly by C9orf85 expression — SKIN

Explore this box plot interactively →