C9orf64

Across TCGA cell cohorts, C9orf64 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible C9orf64-associated genes across cancer lineages are MAGEB4, IL17A, and OR8D4. Each is linked with C9orf64 in more than 1 cancer types. Because this analysis shows association rather than direction, both C9orf64-to-partner and partner-to-C9orf64 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB4 grouped by C9orf64-low versus C9orf64-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf64→partner) and Y-score (partner→C9orf64) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MAGEB4 →	+0.012	+5.415	.009	.004	3	1
STOMACH	IL17A →	+0.040	+5.285	<.001	.003	3	1
STOMACH	OR8D4 →	+0.043	+5.285	<.001	.003	3	1
STOMACH	CT47A6 →	+0.046	+5.285	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

MAGEB4 by C9orf64 expression — LARGE_INTESTINE

Explore this box plot interactively →