C9orf62

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, C9orf62 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C9orf62-associated genes across cancer lineages are Endothelial cells, mv Endothelial cells, and Th1 cells. Each is linked with C9orf62 in more than 1 cancer types. Because this analysis shows association rather than direction, both C9orf62-to-partner and partner-to-C9orf62 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endothelial cells grouped by C9orf62-low versus C9orf62-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf62→partner) and Y-score (partner→C9orf62) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECEndothelial cells →-0.045-3.127.030.02011
UCECmv Endothelial cells →-0.029-3.159.026.02011
UCECTh1 cells →+0.131+3.169.010.02011
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Endothelial cells by C9orf62 expression — UCEC

Box plot of Endothelial cells in C9orf62-low vs C9orf62-high samples in UCEC.

Explore this box plot interactively →

Exploration