Across TCGA patient cohorts, C9orf57 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,094 significant associations in total. STAD shows the largest number of these associations.

The most reproducible C9orf57-associated GO terms across cancer lineages are Regulation of cytokinesis, Obsolete histone modification, and Protein sumoylation. Each is linked with C9orf57 in more than 16 cancer types. Because this analysis shows association rather than direction, both C9orf57-to-partner and partner-to-C9orf57 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf57→partner) and Y-score (partner→C9orf57) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of cytokinesis →	+0.077	+0.172	<.001	.003	3	17
STAD	Obsolete histone modification →	+0.081	+0.277	<.001	<.001	3	16
STAD	Protein sumoylation →	+0.083	+0.252	<.001	<.001	3	15
ESCA	Cytoskeleton-dependent cytokinesis →	+0.071	+0.163	<.001	<.001	3	15
STAD	Nucleus organization →	+0.056	+0.147	<.001	<.001	3	15
ESCA	Cytokinesis →	+0.076	+0.142	<.001	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,094 associations by consensus.

Exploration

C9orf57 survival (RNA) · tumor vs normal (RNA) · all C9orf57 data types