C9orf50

Across TCGA cell cohorts, C9orf50 protein abundance is significantly associated with the RNA expression of many other genes, with 705 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C9orf50-associated genes across cancer lineages are MYH9, CERK, and FUCA2. Each is linked with C9orf50 in more than 1 cancer types. Because this analysis shows association rather than direction, both C9orf50-to-partner and partner-to-C9orf50 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C9orf50 versus MYH9 in BLOOD_Leukemia, with a Pearson correlation of -0.88.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf50→partner) and Y-score (partner→C9orf50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MYH9 →	-1.177	-2.127	.006	.008	3	2
BLOOD_Leukemia	CERK →	-1.237	-2.090	.002	.008	3	2
BLOOD_Leukemia	FUCA2 →	+5.082	+1.849	<.001	<.001	3	2
BLOOD_Leukemia	MS4A6A →	+3.407	+1.680	.004	.002	3	2
BLOOD_Leukemia	CXCR4 →	-7.130	-1.557	<.001	.007	3	2
BLOOD_Leukemia	IRF1 →	-2.081	-1.545	.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 705 associations by consensus.

C9orf50 vs MYH9 — BLOOD_Leukemia

Explore this scatter interactively →