C9orf50

Across TCGA cell cohorts, C9orf50 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C9orf50-associated genes across cancer lineages are C20orf85, LMX1A, and SOX14. Each is linked with C9orf50 in more than 1 cancer types. Because this analysis shows association rather than direction, both C9orf50-to-partner and partner-to-C9orf50 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C20orf85 grouped by C9orf50-low versus C9orf50-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf50→partner) and Y-score (partner→C9orf50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	C20orf85 →	+0.042	+4.969	<.001	.003	3	1
BLOOD_Leukemia	LMX1A →	+0.219	+4.409	<.001	.005	3	1
BLOOD_Leukemia	SOX14 →	+0.007	+5.269	<.001	<.001	3	1
BLOOD_Leukemia	MUC7 →	+0.223	+4.152	<.001	.009	3	1
BLOOD_Leukemia	ADIG →	+0.022	+5.569	<.001	.001	3	1
BLOOD_Leukemia	RTL4 →	+0.021	+4.152	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

C20orf85 by C9orf50 expression — BLOOD_Leukemia

Explore this box plot interactively →