C9orf43

Across TCGA patient cohorts, C9orf43 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,375 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C9orf43-associated proteins across cancer lineages are MTA1, WRNIP1, and NRBF2. Each is linked with C9orf43 in more than 5 cancer types. Because this analysis shows association rather than direction, both C9orf43-to-partner and partner-to-C9orf43 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C9orf43 versus MTA1 in LSCC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf43→partner) and Y-score (partner→C9orf43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MTA1 →	+0.422	+0.524	<.001	<.001	3	6
LSCC	WRNIP1 →	+0.334	+0.433	<.001	<.001	3	5
CCRCC	NRBF2 →	-0.553	-0.400	<.001	<.001	3	5
LSCC	STRBP →	+0.661	+0.503	<.001	<.001	3	5
LSCC	WDR5 →	+0.288	+0.455	<.001	<.001	3	4
LSCC	ZNF318_S136 →	+0.386	+0.304	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,375 associations by consensus.

C9orf43 vs MTA1 — LSCC

Explore this scatter interactively →