C9orf43

Across TCGA patient cohorts, C9orf43 mutation is significantly associated with the RNA expression of many other genes, with 2,632 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C9orf43-associated genes across cancer lineages are RN7SKP68, RNA5SP411, and LINC02612. Each is linked with C9orf43 in more than 1 cancer types. Because this analysis shows association rather than direction, both C9orf43-to-partner and partner-to-C9orf43 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP68 grouped by C9orf43-low versus C9orf43-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf43→partner) and Y-score (partner→C9orf43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SKP68 →	+0.101	+4.070	.007	.009	3	2
UCEC	RNA5SP411 →	+0.894	+1.978	<.001	.002	3	2
BRCA	LINC02612 →	+0.062	+3.504	.007	.005	3	2
BLCA	RNA5SP424 →	+0.234	+4.562	<.001	.006	3	2
BLCA	OR7E23P →	+0.045	+3.840	.001	.006	3	2
BLCA	RPL7L1P4 →	+0.039	+4.433	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,632 associations by consensus.

RN7SKP68 by C9orf43 expression — COAD

Explore this box plot interactively →