C9orf43

Across TCGA cell cohorts, C9orf43 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,482 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible C9orf43-associated GO terms across cancer lineages are Spliceosomal tri-snRNP complex assembly, Response to hydroxyurea, and Double-strand break repair. Each is linked with C9orf43 in more than 7 cancer types. Because this analysis shows association rather than direction, both C9orf43-to-partner and partner-to-C9orf43 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spliceosomal tri-snRNP complex assembly grouped by C9orf43-low versus C9orf43-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf43→partner) and Y-score (partner→C9orf43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Spliceosomal tri-snRNP complex assembly →	+0.082	+0.410	<.001	<.001	3	8
SOFT_TISSUE	Response to hydroxyurea →	+0.091	+0.364	<.001	.001	3	8
SOFT_TISSUE	Double-strand break repair →	+0.071	+0.372	<.001	.002	3	8
CNS	DNA-templated transcription elongation →	+0.059	+0.398	<.001	<.001	3	8
PANCREAS	RNA localization →	+0.058	+0.252	.009	.006	3	8
CNS	Spliceosomal snRNP assembly →	+0.069	+0.399	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,482 associations by consensus.

Spliceosomal tri-snRNP complex assembly by C9orf43 expression — OVARY

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