C9orf24

Across TCGA patient cohorts, C9orf24 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible C9orf24-associated genes across cancer lineages are Neutrophils and Th2 cells. Each is linked with C9orf24 in more than 2 cancer types. Because this analysis shows association rather than direction, both C9orf24-to-partner and partner-to-C9orf24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neutrophils grouped by C9orf24-low versus C9orf24-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf24→partner) and Y-score (partner→C9orf24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Neutrophils →	+0.020	+3.439	.012	.020	3	3
UCEC	Th2 cells →	+0.296	+3.000	.004	.037	2	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Neutrophils by C9orf24 expression — SKCM

Explore this box plot interactively →