C9orf24

Across TCGA cell cohorts, C9orf24 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,083 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible C9orf24-associated GO terms across cancer lineages are Aerobic electron transport chain, Electron transport chain, and Regulation of myoblast fusion. Each is linked with C9orf24 in more than 5 cancer types. Because this analysis shows association rather than direction, both C9orf24-to-partner and partner-to-C9orf24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic electron transport chain grouped by C9orf24-low versus C9orf24-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf24→partner) and Y-score (partner→C9orf24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Aerobic electron transport chain →	+0.085	+0.427	.001	<.001	3	6
BREAST	Electron transport chain →	+0.067	+0.277	.002	.007	3	6
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.096	+0.536	<.001	.007	3	6
PANCREAS	Glycoprotein catabolic process →	+0.105	+0.620	.001	.003	3	6
OVARY	ATP synthesis coupled electron transport →	+0.087	+0.358	.001	.009	3	6
OVARY	Mitochondrial ATP synthesis coupled electron transport →	+0.087	+0.358	.001	.009	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,083 associations by consensus.

Aerobic electron transport chain by C9orf24 expression — OVARY

Explore this box plot interactively →