Across TCGA cell cohorts, C9orf163 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible C9orf163-associated genes across cancer lineages are KCNA5, TBC1D21, and KCNG4. Each is linked with C9orf163 in more than 1 cancer types. Because this analysis shows association rather than direction, both C9orf163-to-partner and partner-to-C9orf163 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf163→partner) and Y-score (partner→C9orf163) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	KCNA5 →	+0.011	+4.095	<.001	.009	3	1
LARGE_INTESTINE	TBC1D21 →	+0.015	+5.022	<.001	.002	3	1
LARGE_INTESTINE	KCNG4 →	+0.004	+4.415	<.001	.007	3	1
LARGE_INTESTINE	FAM71B →	+0.005	+5.022	<.001	.002	3	1
LARGE_INTESTINE	CCER1 →	+0.017	+5.562	<.001	<.001	3	1
LARGE_INTESTINE	OR8G1 →	+0.049	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

C9orf163 survival (RNA) · tumor vs normal (RNA) · all C9orf163 data types