Across TCGA patient cohorts, C9orf135 protein abundance is significantly associated with the protein abundance of many other proteins, with 514 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible C9orf135-associated proteins across cancer lineages are ATXN2_S733, ABCB1, and RNPC3. Each is linked with C9orf135 in more than 1 cancer types. Because this analysis shows association rather than direction, both C9orf135-to-partner and partner-to-C9orf135 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf135→partner) and Y-score (partner→C9orf135) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ATXN2_S733 →	-0.945	-0.858	<.001	<.001	3	1
LUAD	ABCB1 →	-0.813	-0.858	.001	<.001	3	1
LUAD	RNPC3 →	+0.386	+0.963	<.001	.001	3	1
LUAD	SDAD1_S585 →	-0.702	-0.858	.003	<.001	3	1
LUAD	ZFYVE27_S16 →	+0.593	+0.815	.001	.001	3	1
LUAD	MFF →	-0.606	-0.963	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 514 associations by consensus.

Exploration

C9orf135 survival (RNA) · tumor vs normal (RNA) · all C9orf135 data types