Across TCGA pan-cancer cohorts, C9orf135-DT RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated C9orf135-DT data layer.
The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher C9orf135-DT RNA is associated with better overall survival. In most high-consensus cancer types, elevated C9orf135-DT expression acts as an unfavorable survival marker, although some lineages such as OV and PRAD show a favorable association.
OV, MESO, and LGG are the cancer types where C9orf135-DT RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.