Across TCGA patient cohorts, C9orf129 mutation is significantly associated with the RNA expression of many other genes, with 475 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C9orf129-associated genes across cancer lineages are SFPQP1, SEPTIN14P19, and TAB3P1. Each is linked with C9orf129 in more than 1 cancer types. Because this analysis shows association rather than direction, both C9orf129-to-partner and partner-to-C9orf129 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C9orf129→partner) and Y-score (partner→C9orf129) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SFPQP1 →	+0.088	+3.491	<.001	.003	3	2
SKCM	SEPTIN14P19 →	+0.029	+4.147	<.001	.008	3	1
SKCM	TAB3P1 →	+0.039	+4.612	.001	<.001	3	1
SKCM	SETP11 →	+0.065	+3.491	<.001	.003	3	1
SKCM	FCF1P3 →	+0.094	+3.300	.003	.004	3	1
SKCM	TRPC7-AS1 →	+0.191	+3.333	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 475 associations by consensus.

Exploration

C9orf129 survival (RNA) · tumor vs normal (RNA) · all C9orf129 data types