C9

Across TCGA patient cohorts, C9 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,738 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible C9-associated proteins across cancer lineages are NT5E, PXN, and CAPZB. Each is linked with C9 in more than 4 cancer types. Because this analysis shows association rather than direction, both C9-to-partner and partner-to-C9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C9 versus NT5E in LSCC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C9→partner) and Y-score (partner→C9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NT5E →	+0.743	+1.143	<.001	<.001	3	5
HNSC	PXN →	+0.304	+0.936	<.001	.005	3	4
LSCC	CAPZB →	+0.231	+0.980	<.001	<.001	3	4
LSCC	DHX30 →	-0.288	-0.943	<.001	<.001	3	4
GBM	LUZP1 →	+0.358	+0.481	<.001	.006	3	4
GBM	COL6A2 →	+0.896	+0.319	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,738 associations by consensus.

C9 vs NT5E — LSCC

Explore this scatter interactively →