C9

Across TCGA patient cohorts, C9 protein abundance is significantly associated with the RNA expression of many other genes, with 14,654 significant associations in total. GBM shows the largest number of these associations.

The most reproducible C9-associated genes across cancer lineages are COL1A1, FLT1, and SERPINE1. Each is linked with C9 in more than 8 cancer types. Because this analysis shows association rather than direction, both C9-to-partner and partner-to-C9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C9 versus COL1A1 in COAD, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C9→partner) and Y-score (partner→C9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	COL1A1 →	+1.758	+0.625	<.001	.004	3	9
COAD	FLT1 →	+0.873	+1.093	<.001	<.001	3	8
COAD	SERPINE1 →	+1.243	+0.754	<.001	<.001	3	8
GBM	MMP19 →	+1.328	+0.722	<.001	<.001	3	8
CCRCC	PTGIS →	+1.473	+0.552	<.001	.003	3	8
BRCA	CD93 →	+0.973	+0.703	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,654 associations by consensus.

C9 vs COL1A1 — COAD

Explore this scatter interactively →