C8orf88

Across TCGA cell cohorts, C8orf88 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,072 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible C8orf88-associated GO terms across cancer lineages are Protein localization to nucleus, Paranodal junction assembly, and Cellular response to muramyl dipeptide. Each is linked with C8orf88 in more than 9 cancer types. Because this analysis shows association rather than direction, both C8orf88-to-partner and partner-to-C8orf88 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to nucleus grouped by C8orf88-low versus C8orf88-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C8orf88→partner) and Y-score (partner→C8orf88) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Protein localization to nucleus →	+0.040	+1.826	<.001	<.001	3	10
BLOOD_Leukemia	Paranodal junction assembly →	-1.042	-1.740	<.001	.001	3	9
PANCREAS	Cellular response to muramyl dipeptide →	+0.161	+2.137	<.001	<.001	3	9
LUNG_SCLC	Response to alcohol →	-0.055	-1.768	<.001	<.001	3	9
SKIN	DNA replication →	+0.077	+1.455	<.001	<.001	3	9
SKIN	DNA damage tolerance →	+0.061	+1.160	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,072 associations by consensus.

Protein localization to nucleus by C8orf88 expression — BLOOD_Leukemia

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