C8orf88

Across TCGA pan-cancer cohorts, C8orf88 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated C8orf88 data layer compared with 2 for mutation status.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher C8orf88 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated C8orf88 expression acts as an unfavorable survival marker, although some lineages such as UCS and THYM show a favorable association.

BLCA, OV, and LGG are the cancer types where C8orf88 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	All	0.537	0.683	<.001	133	view →
OV	DFS	Median	III,IV	0.112	0.192	.002	66	view →
LGG	OS	Median	All	0.316	0.579	<.001	54	view →
STAD	OS	Quartile	II,III,IV	0.419	0.722	.004	52	view →
KICH	DFS	Median	II,III,IV	0.558	1.000	.003	47	view →
UCS	OS	Median	II,III,IV	0.740	0.456	.013	30	view →
THYM	OS	Median	All	0.960	0.773	.005	25	view →
KIRP	DFS	Tertile	IV	0.034	0.762	.026	24	view →
READ	OS	Quartile	II,III,IV	0.464	0.817	.011	21	view →
UCEC	DFS	Quartile	All	0.773	0.888	.001	18	view →
LIHC	OS	Tertile	All	0.442	0.669	.011	17	view →
SKCM	DFS	Quartile	IV	0.069	0.726	.017	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

C8orf88–BLCA (OS)

Open the BLCA breakdown →