Across TCGA pan-cancer cohorts, C8orf86 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated C8orf86 data layer compared with 16 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher C8orf86 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated C8orf86 expression acts as an unfavorable survival marker.

HNSC and BLCA are the cancer types where C8orf86 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.029	0.751	<.001	48	view →
BLCA	OS	Median	All	0.111	0.720	<.001	24	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: C8orf86 tumor-vs-normal RNA expression · all C8orf86 data types