Across TCGA patient cohorts, C8orf86 mutation is significantly associated with the RNA expression of many other genes, with 459 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C8orf86-associated genes across cancer lineages are RN7SKP236, MIR4472-2, and RN7SL837P. Each is linked with C8orf86 in more than 1 cancer types. Because this analysis shows association rather than direction, both C8orf86-to-partner and partner-to-C8orf86 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C8orf86→partner) and Y-score (partner→C8orf86) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RN7SKP236 →	+0.118	+7.640	<.001	.009	3	2
COAD	MIR4472-2 →	+1.563	+5.893	<.001	.002	3	2
SKCM	RN7SL837P →	+0.183	+6.993	<.001	<.001	3	2
UCEC	RN7SL134P →	+0.145	+2.751	<.001	.002	3	2
UCEC	SNRPCP20 →	+0.321	+3.048	<.001	<.001	3	2
UCEC	RPL7AP69 →	+0.071	+2.376	.003	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 459 associations by consensus.

Exploration

C8orf86 survival (RNA) · tumor vs normal (RNA) · all C8orf86 data types