Across TCGA cell cohorts, C8orf86 RNA expression is significantly associated with the go_rna of many other GO terms, with 692 significant associations in total. BONE shows the largest number of these associations.

The most reproducible C8orf86-associated GO terms across cancer lineages are Membrane fusion, Negative regulation of regulatory T cell differentiation, and Positive regulation of cell-substrate junction organization. Each is linked with C8orf86 in more than 3 cancer types. Because this analysis shows association rather than direction, both C8orf86-to-partner and partner-to-C8orf86 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C8orf86→partner) and Y-score (partner→C8orf86) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Membrane fusion →	+0.034	+0.018	.001	<.001	3	4
BLOOD_Leukemia	Negative regulation of regulatory T cell differentiation →	+0.079	+0.015	.003	.005	3	3
LARGE_INTESTINE	Positive regulation of cell-substrate junction organization →	+0.057	+0.025	.004	.003	3	3
LARGE_INTESTINE	Regulation of receptor localization to synapse →	+0.106	+0.036	<.001	<.001	3	3
LARGE_INTESTINE	Zinc ion import into Golgi lumen →	-0.056	-0.016	<.001	.002	3	3
LARGE_INTESTINE	Protein-containing complex remodeling →	+0.078	+0.014	.003	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 692 associations by consensus.

Exploration

C8orf86 survival (RNA) · tumor vs normal (RNA) · all C8orf86 data types