C8orf49

Across TCGA patient cohorts, C8orf49 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,409 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible C8orf49-associated GO terms across cancer lineages are Negative regulation of chromosome organization, Regulation of chromosome segregation, and Protein localization to condensed chromosome. Each is linked with C8orf49 in more than 11 cancer types. Because this analysis shows association rather than direction, both C8orf49-to-partner and partner-to-C8orf49 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of chromosome organization grouped by C8orf49-low versus C8orf49-high in LIHC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C8orf49→partner) and Y-score (partner→C8orf49) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	Negative regulation of chromosome organization →	+0.033	+0.552	<.001	<.001	3	12
LIHC	Regulation of chromosome segregation →	+0.040	+0.572	<.001	<.001	3	11
LIHC	Protein localization to condensed chromosome →	+0.046	+0.582	<.001	<.001	3	10
KIRP	Microtubule organizing center organization →	+0.030	+0.074	<.001	<.001	3	10
LIHC	Regulation of sister chromatid segregation →	+0.038	+0.576	<.001	<.001	3	10
LIHC	Mitotic nuclear division →	+0.030	+0.530	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,409 associations by consensus.

Negative regulation of chromosome organization by C8orf49 expression — LIHC

Explore this box plot interactively →