C8orf48

Across TCGA patient cohorts, C8orf48 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,985 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible C8orf48-associated proteins across cancer lineages are PHLDB1, SFRP2, and TIMP2. Each is linked with C8orf48 in more than 5 cancer types. Because this analysis shows association rather than direction, both C8orf48-to-partner and partner-to-C8orf48 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C8orf48 versus PHLDB1 in LSCC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C8orf48→partner) and Y-score (partner→C8orf48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PHLDB1 →	+0.544	+0.686	<.001	<.001	3	6
COAD	SFRP2 →	+1.494	+0.520	<.001	<.001	3	5
LSCC	TIMP2 →	+0.552	+0.563	<.001	<.001	3	5
LSCC	PPIF →	-0.496	-0.492	.001	<.001	3	5
LSCC	PARVA →	+0.528	+0.585	<.001	<.001	3	5
LSCC	ENAH →	+0.369	+0.515	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,985 associations by consensus.

C8orf48 vs PHLDB1 — LSCC

Explore this scatter interactively →