C8orf37

Across TCGA patient cohorts, C8orf37 mutation is significantly associated with the RNA expression of many other genes, with 44 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible C8orf37-associated genes across cancer lineages are SLC16A12-AS1, MTND1P3, and RPL23AP40. Each is linked with C8orf37 in more than 1 cancer types. Because this analysis shows association rather than direction, both C8orf37-to-partner and partner-to-C8orf37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC16A12-AS1 grouped by C8orf37-low versus C8orf37-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C8orf37→partner) and Y-score (partner→C8orf37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SLC16A12-AS1 →	+0.055	+5.469	<.001	.002	3	1
SKCM	MTND1P3 →	+0.051	+4.470	.004	.005	3	1
SKCM	RPL23AP40 →	+0.114	+4.628	.007	.004	3	1
SKCM	RPL7AP56 →	+0.049	+4.771	<.001	.006	3	1
SKCM	RN7SL870P →	+0.171	+5.682	<.001	<.001	3	1
BLCA	IGKV2D-10 →	+0.292	+5.106	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

SLC16A12-AS1 by C8orf37 expression — SKCM

Explore this box plot interactively →