C8orf34-AS1

Across TCGA pan-cancer cohorts, C8orf34-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated C8orf34-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher C8orf34-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated C8orf34-AS1 expression acts as an unfavorable survival marker, although some lineages such as MESO and BRCA show a favorable association.

MESO, SKCM, and LUSC are the cancer types where C8orf34-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Median	All	0.529	0.256	<.001	80	view →
SKCM	DFS	Tertile	III,IV	0.317	0.545	<.001	78	view →
LUSC	DFS	Tertile	II,III,IV	0.629	0.838	<.001	72	view →
HNSC	OS	Median	III,IV	0.372	0.710	<.001	66	view →
BLCA	DFS	Median	All	0.169	0.478	<.001	57	view →
LIHC	OS	Tertile	All	0.285	0.590	.001	36	view →
LGG	DFS	Quartile	All	0.752	0.874	.001	34	view →
BRCA	OS	Quartile	III,IV	0.885	0.729	.008	30	view →
KICH	DFS	Median	II,III,IV	0.570	0.920	.005	30	view →
UVM	DFS	Tertile	All	0.364	0.783	.017	27	view →
COAD	OS	Quartile	All	0.946	0.776	.009	20	view →
LUAD	OS	Quartile	All	0.613	0.290	.013	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

C8orf34-AS1–MESO (DFS)

Open the MESO breakdown →