C8orf17

Across TCGA pan-cancer cohorts, C8orf17 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of C8orf17’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where C8orf17 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types C8orf17 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

KIRC, THCA, and BRCA are the cancer types where C8orf17 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in C8orf17 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	III,IV	+0.074	<.001	10	view →
THCA	All	All	−0.016	.013	4	view →
BRCA	All	All	+0.098	.046	2	view →
STAD	Male	All	+0.059	.009	2	view →
CHOL	All	All	+0.028	.043	1	view →
HNSC	Male	All	+0.008	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

C8orf17–KIRC

Open the KIRC breakdown →