C8A

Across TCGA cell cohorts, C8A RNA expression is significantly associated with the go_rna of many other GO terms, with 440 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible C8A-associated GO terms across cancer lineages are Reproductive structure development, Reproductive system development, and Response to catecholamine. Each is linked with C8A in more than 2 cancer types. Because this analysis shows association rather than direction, both C8A-to-partner and partner-to-C8A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Reproductive structure development grouped by C8A-low versus C8A-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C8A→partner) and Y-score (partner→C8A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Reproductive structure development →	+0.071	+0.005	.001	.007	3	3
LUNG_NSCLC_LUAD	Reproductive system development →	+0.073	+0.003	.001	.008	3	3
LIVER	Response to catecholamine →	+0.096	+1.028	.008	.007	3	2
LIVER	Cellular response to toxic substance →	+0.131	+1.245	<.001	<.001	3	2
LIVER	Detoxification →	+0.114	+1.107	<.001	.003	3	2
LUNG_NSCLC_LUAD	Regulation of plasma cell differentiation →	+0.115	+0.003	.005	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 440 associations by consensus.

Reproductive structure development by C8A expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →