C7orf77

Across TCGA patient cohorts, C7orf77 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,543 significant associations in total. STAD shows the largest number of these associations.

The most reproducible C7orf77-associated GO terms across cancer lineages are Negative regulation of innate immune response, Viral genome replication, and Peptide antigen assembly with MHC protein complex. Each is linked with C7orf77 in more than 13 cancer types. Because this analysis shows association rather than direction, both C7orf77-to-partner and partner-to-C7orf77 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of innate immune response grouped by C7orf77-low versus C7orf77-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C7orf77→partner) and Y-score (partner→C7orf77) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of innate immune response →	+0.072	+0.213	<.001	<.001	3	14
ESCA	Viral genome replication →	+0.066	+0.106	<.001	.001	3	12
ESCA	Peptide antigen assembly with MHC protein complex →	+0.127	+0.234	<.001	.004	2	13
ESCA	Regulation of antigen processing and presentation of peptide antigen →	+0.051	+0.170	<.001	.005	2	13
STAD	Negative regulation of response to biotic stimulus →	+0.059	+0.112	<.001	<.001	3	12
STAD	Response to protozoan →	+0.049	+0.142	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,543 associations by consensus.

Negative regulation of innate immune response by C7orf77 expression — STAD

Explore this box plot interactively →