C7orf77

Across TCGA cell cohorts, C7orf77 RNA expression is significantly associated with the mutation status of many other genes, with 103 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible C7orf77-associated genes across cancer lineages are MXRA5, SOS1, and MEGF8. Each is linked with C7orf77 in more than 1 cancer types. Because this analysis shows association rather than direction, both C7orf77-to-partner and partner-to-C7orf77 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MXRA5 grouped by C7orf77-low versus C7orf77-high in PANCREAS.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C7orf77→partner) and Y-score (partner→C7orf77) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	MXRA5 →	+4.614	+0.035	.004	<.001	3	2
LUNG_NSCLC_LUAD	SOS1 →	+4.662	+0.046	.005	<.001	3	2
PANCREAS	MEGF8 →	+4.614	+0.035	.004	<.001	3	1
PANCREAS	YLPM1 →	+5.614	+0.046	.002	<.001	3	1
PANCREAS	OR4A15 →	+5.614	+0.046	.002	<.001	3	1
PANCREAS	SCN8A →	+5.614	+0.046	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 103 associations by consensus.

MXRA5 by C7orf77 expression — PANCREAS

Explore this box plot interactively →