C7orf69

Across TCGA patient cohorts, C7orf69 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,685 significant associations in total. STAD shows the largest number of these associations.

The most reproducible C7orf69-associated GO terms across cancer lineages are Negative regulation of cell activation, Negative regulation of lymphocyte activation, and Alpha-beta T cell proliferation. Each is linked with C7orf69 in more than 17 cancer types. Because this analysis shows association rather than direction, both C7orf69-to-partner and partner-to-C7orf69 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell activation grouped by C7orf69-low versus C7orf69-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (C7orf69→partner) and Y-score (partner→C7orf69) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Negative regulation of cell activation →	+0.053	+0.180	<.001	<.001	3	18
ESCA	Negative regulation of lymphocyte activation →	+0.053	+0.161	.001	<.001	3	18
ESCA	Alpha-beta T cell proliferation →	+0.050	+0.135	<.001	<.001	3	18
STAD	Fibroblast migration →	+0.046	+0.168	<.001	<.001	3	17
ESCA	Activation of innate immune response →	+0.053	+0.186	<.001	<.001	3	17
ESCA	Negative regulation of cell-cell adhesion →	+0.048	+0.174	.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,685 associations by consensus.

Negative regulation of cell activation by C7orf69 expression — ESCA

Explore this box plot interactively →