C7orf69

Across TCGA pan-cancer cohorts, C7orf69 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated C7orf69 data layer compared with 3 for mass-spec protein.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher C7orf69 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated C7orf69 expression acts as an unfavorable survival marker, although some lineages such as COAD and ESCA show a favorable association.

CHOL, LUSC, and STAD are the cancer types where C7orf69 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CHOL	DFS	Tertile	III,IV	0.031	0.505	.003	117	view →
LUSC	OS	Median	All	0.337	0.453	.023	21	view →
STAD	DFS	Tertile	All	0.585	0.824	.006	18	view →
COAD	OS	Median	IV	0.816	0.280	.007	16	view →
PAAD	DFS	Quartile	All	0.174	0.446	.009	15	view →
ESCA	DFS	Quartile	II,III,IV	0.419	0.225	.024	13	view →
DLBC	DFS	Median	All	0.332	0.919	.008	11	view →
THCA	OS	Tertile	IV	0.813	1.000	.039	9	view →
SCLC	OS	Tertile	III,IV	0.416	0.673	.045	9	view →
SKCM	DFS	Median	IV	0.763	0.187	.006	9	view →
KIRP	DFS	Tertile	All	0.850	0.926	.025	9	view →
SARC	OS	Quartile	All	0.714	0.904	.006	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

C7orf69–CHOL (DFS)

Open the CHOL breakdown →